Posted May 5, 2026
Who We Are:
Calico (Calico Life Sciences LLC) is an Alphabet-founded research and development company whose mission is to harness advanced technologies and model systems to increase our understanding of the biology that controls human aging. Calico will use that knowledge to devise interventions that enable people to lead longer and healthier lives. Calico’s highly innovative technology labs, its commitment to curiosity-driven discovery science and, with academic and industry partners, its vibrant drug-development pipeline, together create an inspiring and exciting place to catalyze and enable medical breakthroughs. Position Description:
We are seeking a highly skilled in vivo scientist to significantly advance neurodegenerative disease research, with a focus on Parkinson's disease. The individual will be instrumental in designing, executing, and interpreting experiments using rodent models to investigate neurological and aging disorders and evaluate therapeutic interventions. This will enhance the Translational Neuroscience team's in vivo research capacity, establish advanced models for due diligence, and test novel drug mechanisms of action. The scientist will also be crucial in modeling novel aspects of neurodegenerative diseases, incorporating human cohort findings, and setting up mechanistic models to test hypotheses from new target discovery. :
Position Requirements:
Ph.D. in Neuroscience, Biology, Pharmacology, or a related field, with 5+ years relevant postdoctoral or equivalent industrial experience
In Vivo Expertise:
Experience in live animal surgeries
Extensive experience with broad animal behavioral assessment techniques
Expertise in rodent handling, compound treatments, micro sampling, and CNS tissue harvests
Experience in longitudinal monitoring of behavior and colony maintenance
Laboratory Skills:
Practical experience in cellular assays
Skilled in cells and tissue immunohistochemistry and microscopy, including basic histological techniques for tissue processing, staining, and image analysis
Analytical & Communication Skills:
Excellent communication, interpersonal, and organizational skills
Ability to work independently and collaboratively within multidisciplinary team
Meticulous with attention to detail
Must be willing to work onsite 5 days a week
The estimated base salary range for this role is $166,000 - $191,000. Actual pay will be based on a number of factors including experience and qualifications. This position is also eligible for two annual cash bonuses. ##
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