Cogent Biosciences is a publicly traded biotechnology company focused on developing novel precision therapies to treat a broad range of patients with unmet medical needs. Cogent’s lead program, bezuclastinib, is designed to selectively and potently inhibit exon 17 mutations found within the KIT receptor tyrosine kinase, including KIT D816V. KIT D816V is responsible for driving a rare and serious condition called Systemic Mastocytosis, and exon 17 mutations are also found in patients with gastrointestinal stromal tumors (GIST), a type of cancer with strong dependence on oncogenic KIT signaling. Bezuclastinib has exhibited promising initial data across all three trials: APEX in AdvSM, SUMMIT in NonAdvSM and PEAK in GIST, including an encouraging safety profile across 600+ patients in single agent and combination dosing. ---
The Role: The Senior Manager of Trade and Distribution will be responsible for management of Cogent Bioscience’s network of Specialty Distributor accounts. The Key responsibilities will be to oversee the physical and financial flow of the Cogent Biosciences portfolio beginning with the launch of Bezuclastinib. The candidate will be the primary for Specialty Distributor customers tasked with maintaining relationships and growing Cogent Biosciences business while contributing to the evolving channel strategy for products. This candidate will oversee all aspects of business operations within assigned customers including inventory management, product fulfillment, data flow and management of returns. The individual will report to the Executive Director Trade & Distribution within the Market Access team and work closely with Corporate Accounts, Payer Accounts, Field Sales, Patient Access Services and Commercial Operations as well as other internal Cogent Biosciences colleagues. ---
Responsibilities:
Strategic Relationship Management- Serve as the primary point of contact for 5 core specialty distributors. Lead quarterly business reviews, negotiate fee for service agreements and monitor contract compliance. - Sustain long-term customer partnerships with assigned accounts, based on a deep understanding of the customer organization, structure, business strategy, and priorities. - Ability to build effective business plans that align with access goals to support brand and market access strategies. - Develop contract negotiation and execution strategies with leadership team, including pre-contract financial ROI analysis, contract language negotiation, execution, post contract measurement and analysis. - Supply Chain Integrity-Ensure seamless distribution of high value products and manage inventory to ensure patient access. - Data & Analytics- Monitor 852/867 data feeds to track product movement, inventory levels and channel pull through. - Cross Functional Collaboration- Partner with colleagues from Market Access, Supply Chain, Commercial Ops, Quality, Patient Services and Marketing to ensure distribution model supports the overall patient journey and brand strategy. - Trade Operations- Oversee the order to cash process, manage chargebacks, returns and any distribution related discrepancies within customers. - Ensure strategies and KPIs are implemented and monitored to achieve our commercial goals while working within the assigned budget. - Works within Cogent’s compliance policies. - This is a hybrid role and the candidate will need to be in the Waltham MA office 2 days per week. ---
Qualifications:
Bachelor’s degree required. Master’s degree, MBA or RPh a plus
5-8 years of pharmaceutical trade & distribution experience with a heavy preference for rare disease or oncology experience within specialty. - 5+ of experience in related fields such as Market Access, Wholesaler or Specialty Pharmacy account management, 3PL management or distribution & supply chain management in pharmaceutical / biotech companies. Knowledge / Skills Needed:
Understanding of the current healthcare landscape, compliant manufacturer practices surrounding promotion, 3Rd Party Logistics, product distribution, and product fulfillment
Ability to build strong customer relationships, strategic planning and influencing skills
Strong analytical skills with a proven ability to effectively analyze data to determine trends and inform strategy
Knowledge of data flow, chargeback management and or DSCSA requirements
Excellent verbal and written communication skills
Proficient in Microsoft Excel, Word, and PowerPoint
Demonstrated leadership and management skills
Ability to manage up to 50% domestic travel
Personal Attributes Needed:
Ability to engage with customers and resolve product fulfillment issues or challenges
Demonstrated ability to develop effective / collaborative working relationships with Field teams, Brand teams and home office functions
Ability to understand business requirements, market dynamics and propose solutions, gain alignment and execute
Proven ability to identify issues and provide effective solutions to address them. Ability to effectively communicate the solution and its value to affected parties. - Ability to work with multiple customers simultaneously
Ability to learn and work autonomously
Salary Range:
$175k-205k USD
Target Bonus: 15%
Exact compensation will vary based on skills, experience, and location. ---
Our Locations
Waltham, MA: Our headquarters is located in the Greater Boston life sciences community, with an open, collaborative office environment designed to support teamwork and connection. Employees benefit from convenient on-site amenities, including free on-site parking and gym facilities in the building. Boulder, CO: Our Boulder location is home to Cogent’s discovery research organization and a key scientific hub with strong leadership based on site. Situated in the greater Denver-Boulder biopharmaceutical corridor, this office plays a central role in advancing our discovery efforts and pipeline. ---
Our Offer To You
At Cogent Biosciences, we offer a competitive salary, bonus, and ongoing stock awards, alongside a benefits package that sets us apart. We cover 100% of medical, dental, and vision premiums for you and your family, and help reduce out-of-pocket costs by funding up to 75% of in-network deductibles. Our benefits also include a 401(k) match with immediate vesting, generous paid time off, 12 weeks of fully paid parental leave, paid family and medical leave for all employees regardless of location, and company-paid short-term disability coverage for up to 20 weeks. Additional perks like wellness programs, tuition reimbursement, and inclusive family-forming support help you thrive at work and beyond. Our goal is to have a diverse workforce. All employment is decided on the basis of qualifications, merit, and business need.
