Posted Apr 1, 2026
KEY RESPONSIBILITIES
Design, synthesize, purify, and characterize chemical compounds (10 mg–5 g scale) using modern analytical techniques such as LCMS, HPLC, and NMR, employing both individual and automated parallel synthesis approaches. - Identify and optimize reaction conditions using screening kits and other streamlined methodologies. - Collaborate with the high-throughput experimentation team to ensure the successful execution of parallel chemistry experiments. - Analyze biological and ADME-PK data using cheminformatics tools and contribute to data-driven discussions and strategic planning. - Partner with computational chemists to leverage machine learning insights for efficient execution of the design–make–test cycle and platform development. - Present results to project teams and senior leadership, clearly communicating data, implications, and recommendations. QUALIFICATIONS
BS in Chemistry with 5+ years experience (pharma/biotech) or MS in Chemistry with 3+ years experience (pharma/biotech). - Proven skills in multi-step organic synthesis, reaction optimization, SAR analysis, and scientific presentation. - Ability to thrive in a fast-paced, highly collaborative research environment. - Availability to work onsite in San Diego. PREFERRED QUALIFICATIONS
Prior exposure to high-throughput experimentation. - Familiarity with ADME-PK principles. - 5+ years of experience contributing to drug discovery projects. - Experience with molecular modeling and structure-based drug design
MISSION & CORE VALUES
Our mission is to deliver better medicines through innovations in AI-based discovery technologies. The culture and work at Iambic Therapeutics are profoundly strengthened by the diversity of our people and our differences in background, culture, national origin, religion, sexual orientation, and life experiences. We are committed to building an inclusive environment where a diverse group of talented humans work together to discover therapeutics and create technologies. PAY AND BENEFITS
We offer industry leading competitive pay, company paid healthcare, flexible spending accounts, voluntary life insurance, 401K matching, and uncapped vacation to our team. We are in a brand-new state-of-the art facility in beautiful San Diego with an onsite gym, dining, and easy access to great places to live and play.
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